Biologics
Latest articlesDiscover our most recent posts across all industries, brands and topics. Fast and Accurate Vehicle Dynamics AssessmentsBy integrating design and simulation, SIMULIA empowers automotive OEMs, startups, race teams and suppliers to innovate faster and more efficiently. Our solutions h
The COVID‑19 pandemic remains a formidable threat to global public health and has disrupted economies worldwide. SARS‑CoV‑2, the virus responsible for the outbreak, is not a typical influenza strain; it targets both upper and lower respiratory tracts, impairing essential breathing processes and caus
“Testing, testing, testing!” has become a rallying cry for COVID‑19 containment. Global health authorities—including the World Health Organization and national agencies—continue to emphasize that rapid, widespread testing is the linchpin of any effective pandemic response. Extensive diagnostic cove
In our previous post, we examined how predictive modeling tools can generate atomic‑level structures of viral proteins and fill in experimentally unresolved regions, such as missing hydrogen atoms and flexible loops. We focused on the cryo‑electron microscopy (cryo‑EM) structure of the SARS‑CoV‑2 sp
Targeting the SARS‑CoV‑2 Main Protease Developing a novel antiviral is both expensive and time‑consuming. In the midst of a global pandemic, the urgent need is to identify drugs that can halt viral replication rapidly. Drug repurposing—leveraging medicines already proven safe in humans—offers a prom
This promotion has ended. Learn more about BIOVIA training courses With more time at home, now is the perfect moment to deepen your expertise in BIOVIA Pipeline Pilot—whether you’re a scientist, developer, or administrator. Eligible Pipeline Pilot customers who are currently under active support can
AI‑Powered Ideation Engine for Biopharma Bringing a novel therapeutic to patients is a costly, time‑consuming endeavor. The average total cost to develop and market a drug is approximately $3 billion, spanning 12–14 years. The discovery phase alone consumes about one‑third of that budget and typica
Drug repurposing—reassigning approved or investigational drugs to new therapeutic uses—has long been a cornerstone of rapid therapeutic discovery.1 Its most celebrated success, the transformation of a hypertension and angina medication into Pfizer’s “little blue pill,” Viagra, showcases its potentia
Mitochondria are the cell’s powerhouses. By oxidizing nutrients, they generate a proton gradient across the inner mitochondrial membrane. This electrochemical “battery” is the direct source of ATP, the universal energy currency of life. What if an “uncoupler” disrupts this finely tuned system? An u
Biotherapeutics have surged to the forefront of pharmaceutical R&D over the last twenty years, delivering transformative outcomes for diseases once deemed untreatable. Their power lies in precision—antibodies and antibody‑like molecules target specific cells with surgical accuracy. By leveraging th
SARS‑CoV‑2 vaccine production has faced delays, leaving many countries short of the doses they contracted. Even a few weeks’ lag can ripple through public health, politics and society. Vaccine manufacturing is a sophisticated, time‑consuming bioprocess that must pass multiple filtration, purificatio
New Directions in the Fight Against COVID‑19 Drug repurposing and systems biology are powerful allies in identifying safe, effective therapies for SARS‑CoV‑2. These approaches also provide a roadmap for tackling future coronavirus threats. Repurposing Safe Drugs in a Global Pandemic Drug repurposin
Date: May 5 @ 11 am ET Manufacturing vaccines and biologics on schedule is critical to public health and commercial viability. From raw‑material sourcing to cell‑culture scale‑up, each step must meet stringent regulatory timelines while maintaining product quality. Key Challenges Supply chain dis
Advanced Prediction of Biomembrane Permeability with COSMOperm How easily can a small molecule—whether a pharmaceutical agent, chemical toxicant, or environmental pollutant—diffuse through a biomembrane? The BIOVIA COSMOperm tool empowers researchers to forecast passive membrane permeabilities for
Biologics
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